Several characters also receive new alternate special attacks different from Gekitō Ninja Taisen! EX 3 to Clash of Ninja Revolution 3, examples include Naruto, Sakura, Gaara, Kankurō, Itachi and Sasori. For example, Kakashi, a mainstay of the series since the first game, has been changed, now sporting a few new moves, combo/string finishers, and several techniques copied from other characters that he can use at any time. It also features what was described as an 'overhauled combat system.' While many characters have already undergone changes due to the time skip in the story, almost every character has had some major changes since their last appearances in the previous game or Naruto Shippūden: Gekitō Ninja Taisen! EX 3.
It covers the Kazekage Rescue Mission in the story mode, as with the first Shippūden game in the Gekitō Ninja Taisen! EX series in Japan, and it is also the first game in the series to have Wi-fi connectivity for online battles. The game boasts a robust roster of 40 playable characters. The European version is slightly different from the American version in that several glitches have been fixed and the in-battle voices for all characters are Japanese, with several new voice clips recorded and even new voice actors cast for some characters. It is the fifth instalment of the Clash of Ninja series and the overall tenth game using the Gekitō Ninja Taisen fighting engine.